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Thursday, April 9, 2026 •                  • 5
                                                                  FDA approves drug for  Hodgkin lymphoma patients 12 and older
                                                                  Approval based on clinical       The  trial  found  that  teens  and  “We  are  excited  about  the
                                                                  trial led by researcher       adults  with  advanced-stage  Hodg- FDA’s  decision  because  it  facili-
                                                                  at UB, Roswell Park           kin lymphoma survive longer with- tates  access  to  nivolumab  for  pa-
                                                                     The Food and Drug Administra-  out their disease coming back when tients 12 years and up,” says Kelly.
                                                                                                they  receive  the  immunotherapy “Plus,  it’s  the  first  time  that  the
                                                                  tion  has  approved  the  immune
                                                                  checkpoint  inhibitor  nivolumab  in  nivolumab  (brand  name  Opdivo) FDA  approved  a  new  drug  for
                                                                                                instead of the immunotherapy bren- Hodgkin lymphoma in pediatric pa-
                                                                  combination with chemotherapy for
                                                                  adults and adolescents 12 and older  tuximab vedotin (brand name Adce- tients  at  the  same  time  that  they
                                                                                                tris)  along  with  chemotherapy. approved it for adults.”
                                                                  with  previously  untreated  Stage
                                                                  III/IV classic Hodgkin lymphoma.  These results, the authors conclud-  She notes that with most cancer
                                                                                                ed, support approving the drug for drugs,  it  has  historically  taken  an
     THERE WAS DANCING, MUSIC AND PLENTY OF FOOD on the              The approval was based on data
     menu  at  Polish  Cadets,  927  Grant  St.  For  its  Dyngus  Day from  a  randomized  clinical  trial  advanced stage Hodgkin lymphoma average of six years after approval
     celebration on April 6.  Photos by Amber Healy               published in the New England Jour-  and  lowering  to  12  the  minimum in adults for a drug to be approved
                                                                  nal  of  Medicine  in  October  2024.  age  for  receiving  nivolumab,  a in children.
                                                                                                checkpoint  inhibitor  that  has  been
                                                                  Earlier  this  year,  the  Journal  of
                                                                  Clinical Oncology published a more  described as “releasing the brakes”
                                                                                                on the immune system.
                                                                  detailed subset analysis of the ado-
                                                                  lescent patients in the study, includ-  Subsequently,   the   National
                                                                                                Comprehensive   Cancer   Center
                                                                  ing  longer  follow-up  data  that
                                                                  confirmed the excellent results with  guidelines — the international gold
                                                                                                standard  for  treatment  recommen-
                                                                  nivolumab.  The  FDA  reviewed  all
                                                                  of these data in making its determi-  dations — for both adult and pediat-
                                                                                                ric  Hodgkin  lymphoma  were
                                                                  nation to approve the drug.
                                                                     Kara  M.  Kelly,  MD,  division  updated to reflect the newly discov-
                                                                                                ered best practice of combining niv-
                                                                  chief of hematology/oncology in the
                                                                  Department  of  Pediatrics,  Jacobs  olumab  with  a  chemotherapy
                                                                                                combination called AVD for adoles-
                                                                  School of Medicine and Biomedical
                                                                  Sciences at the University at Buffa-  cents  and  adults  newly  diagnosed
                                                                                                with stage 3-4 classic Hodgkin lym-
                                                                  lo,  and  chair  of  the  Roswell  Park
                                                                  Golisano  Children’s  Cancer  and  phoma (cHL).
                                                                  Blood  Disorders  Program,  was  se-
                                                                  nior author on the publication that
                                                                  focused on adolescents. She is also
                                                                  Waldemar  J.  Kaminski  Endowed
                                                                  Department Chair of Pediatrics and
                                                                  professor  of  pediatric  oncology  at
                                                                  Roswell Park Comprehensive Can-
                                                                  cer  Center;  Roswell  Park  was  the
                                                                  regional study site through Kelly’s
                                                                  leadership role on the clinical trial.
                                                                  Sharon Castellino, MD, of the Aflac
                                                                  Cancer and Blood Disorders Center
                                                                  of Children’s Healthcare of Atlanta
                                                                  and  Emory  University  School  of
                                                                  Medicine, was first author.





     Sisters of Faith to Host Community

     Meat Raffle at Knox Church
       The Sisters of Faith group at Knox Evangelical Presbyterian Church,           THANK   YOU!
     2595 Kenmore Ave., Kenmore announced a high-stakes Meat Raffle on
     Saturday, April 18, 2026. Organizers say this community event promises
     an  afternoon  of  fun,  food,  and  a  chance  to  win  premium  cuts  of  meat
     provided by Market in the Square.
       Doors open at 2 p.m. with first pull at 3 p.m. Please enter through the
                                                                                          Buffalo Club 49ers Inc.
     Hamilton Street entrance.                                                            Buffalo Club 49ers Inc.
       Tickets are $15 pre-sale; $20 at the door; table of 8 - $100. Each ticket  wish to thank the patrons listed below who contributed to their
     includes a complimentary meal of a hot dog or a slice of pizza and a soda.
     While guests are encouraged to bring their own snacks to enjoy at their  71st Annual Easter Egg Hunt held April 4, 2026 at Riverside Park.
     tables, no alcohol is allowed on the premises.
       The main event will feature 15 to 18 rounds of raffles, with individual   Any omission of a patron’s name is unintentional.
     round tickets ranging from $1 to $5. Participants are strongly encouraged
     to "Bring Your Own Singles" to ensure they are ready for every pull.  K.W. Appliances                                     Francis W. King Petroleum Products
       In addition to the main meat raffle, there will be Basket Raffles featur-  Schmit Plumbing, Heating and AC                           The Hair Place
     ing local goods, a 50/50 Split for a chance at a cash prize, and a Gift Card
     Raffle.                                                          George Washington Fishing and Camping Club     The Unknowns Club
                                                                      Pat’s Pizzeria                                                           Steve Frankowski

                                                                      Enterprise Folding Box Company                 Kevin & Patricia Myers
                                                                      Councilman Joe Golombek Jr                     Rob Williams
                                                                      Black Rock Pharmacy                                          Sue, Dan & Carl Sontag

                                                                      James E. Grace Funeral Home                          Barry’s Social Club
                                                                      Susan Rudnicki                                 Greenpac Mill
                                                                      Daryle Piotrowski Family                       Kolano Funeral Home

                                                                      Christine Hausrath                             Andy Sullivan
                                                                      Jose Morales Jr.


                                                                          Special “Thanks” to the Easter Bunny (Amber Boone). Thanks to all the volunteers
                                                                            who assisted this year and Buffalo Olmstead Conservancy and Buffalo Parks Dept.
                                                                                                   for the use of Riverside Park.

                                                                                                                     BUFFALO
                                                                                                             CLUB ‘49ers, Inc.
                     Coupon Expires 4/30/26                                                                      144 Mayer Avenue
                                                                                                              Buffalo, New York 14207
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